Diffuse large B cell lymphoma: molecular targeted therapy
نویسندگان
چکیده
منابع مشابه
Diffuse large B cell lymphoma: molecular targeted therapy.
Diffuse large B cell lymphoma (DLBCL) is a biologically heterogeneous disease and the most common subtype of B cell non-Hodgkin's lymphoma in the USA. Even though it is a curable lymphoma in advanced stages, up to 40 % of patients eventually relapse or fail to achieve remission. Improved understanding of the biologic complexity of DLBCL reveals a diverse range of oncogenic driver mutations and ...
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Keywords Disease name and synonyms Differential diagnosis Frequency Definition Clinical description Etiology Genetic features Diagnostic methods Staging Prognostic parameters Treatment Survival Keywords References Abstract Primary diffuse large B-cell lymphomas (DLB-CL) are aggressive tumors accounting for approximately 40% of the B-cell malignancies. DLB-CL are commonly composed of a mixture o...
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ژورنال
عنوان ژورنال: International Journal of Hematology
سال: 2012
ISSN: 0925-5710,1865-3774
DOI: 10.1007/s12185-012-1198-3